Zinc (Zn) deficiency and Hepatitis C (HCV)/HIV Co‐infection in HIV+ drug users in Miami

Objective Objective In HIV‐infection, Zn deficiency has been associated with disease progression and increased morbidity and mortality. We studied the association of HIV/HCV co‐infection with Zn deficiency and health indicators in HIV+ drug users. Methods After consenting 207 HIV+ drug users,demogra...

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Bibliographic Details
Published in:The FASEB journal 2006-03, Vol.20 (4), p.A628-A628
Main Authors: Duan, Rui, Baum, Marianna K, Xue, Lihua, Sales, Sabrina, Rafie, Carlin, Page, John B, Campa, Adriana
Format: Article
Language:English
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Summary:Objective Objective In HIV‐infection, Zn deficiency has been associated with disease progression and increased morbidity and mortality. We studied the association of HIV/HCV co‐infection with Zn deficiency and health indicators in HIV+ drug users. Methods After consenting 207 HIV+ drug users,demographic, nutritional, medical and treatment questionnaires and anthropometries were completed. Blood was drawn for CD4 cell counts, HIV viral load, and plasma Zn. Results Of the 207 participants, 37.2% were co‐infected with HCV, 72.5% were males and 63% were on HAART. Mean age was 42 years. Plasma Zn was significantly lower in the co‐infected group (0.61±0.13 mg/L, p=0.041) as compared to those who were not coinfected (0.67±0.15 mg/L) after adjusting for gender, age, macronutrient intake, and HAART. Participants with low Zn plasma (
ISSN:0892-6638
1530-6860
DOI:10.1096/fasebj.20.4.A628-a