Bone Mineral Density and Content: Dual Energy X‐ray Absorptiometry versus Peripheral Quantitative Computed Tomography

Dual energy x‐ray absorptiometry (DXA) assesses bone mineral density (BMD) and content (BMC), but does not differentiate between cortical (Cr) and trabecular (Tb) bone, independent contributors to bone strength and fracture risk. Peripheral quantitative computed tomography (pQCT) provides a 3‐D imag...

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Bibliographic Details
Published in:The FASEB journal 2006-03, Vol.20 (5), p.A1062-A1063
Main Authors: Shedd, K M, Hanson, K B, Alekel, D L, Hanson, L N, Van Loan, M D
Format: Article
Language:English
Online Access:Get full text
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Summary:Dual energy x‐ray absorptiometry (DXA) assesses bone mineral density (BMD) and content (BMC), but does not differentiate between cortical (Cr) and trabecular (Tb) bone, independent contributors to bone strength and fracture risk. Peripheral quantitative computed tomography (pQCT) provides a 3‐D image of bone and assesses Tb and Cr bone. We compared total (To) BMC, TbBMC, volumetric (v) BMD, and TbBMD of the 4% distal tibia, and ToBMC, CrBMC, vBMD, and CrBMD of the 33% midshaft femur using pQCT to lumbar spine (Sp), hip, and femoral neck (FN) BMD and BMC from DXA in healthy, postmenopausal women. Tibia pQCT BMC and BMD measures were highly correlated (p
ISSN:0892-6638
1530-6860
DOI:10.1096/fasebj.20.5.A1062-c