99m Tc-PIPIDA Cholescintigraphy in the Diagnosis of Gallbladder Disease

The efficacy of 99mTc cholescintigraphy in the diagnosis of gallbladder disease was studied in 116 patients. Sixty-one demonstrated gallbladder visualization (normal) and 55 had nonvisualization. In patients with acute abdominal pain, test sensitivity is 100%, specificity is 77%, and accuracy is 83%...

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Bibliographic Details
Published in:The American journal of the medical sciences 1982-11, Vol.284 (3), p.23-31
Main Authors: Rosen, Paul R., Rusing, Thomas W., Nusynowitz, Martin L., Lecklitner, Myron L.
Format: Article
Language:English
Subjects:
Acute cholecystitis
Cholescintigraphy
Chronic cholecystitis
Gallbladder disease
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Summary:The efficacy of 99mTc cholescintigraphy in the diagnosis of gallbladder disease was studied in 116 patients. Sixty-one demonstrated gallbladder visualization (normal) and 55 had nonvisualization. In patients with acute abdominal pain, test sensitivity is 100%, specificity is 77%, and accuracy is 83% for the diagnosis of acute cholecystitis; no patient with gallbladder visualization had acute cholecystitis. Test sensitivity for any form of gallbladder disease is 66%, specificity is 82%, and accuracy is 71%; excluding patients with laboratory evidence of hepatobiliary disease, the predictability of acute or chronic cholecystitis increases to 100%. Cholescintigraphy demonstrated common bile duct patency in all eight post-cholecystectomy patients referred for evaluation of possible choledocholithiasis. Thus, gallbladder visualization with 99mTc-PIPIDA virtually excludes the diagnosis of acute cholecystitis, an abnormal test is a good predictor of gallbladder disease because of high specificity, and cholescintigraphy is extremely safe and simple to perform and may be used to demonstrate common bile duct patency.
ISSN:0002-9629
1538-2990
DOI:10.1097/00000441-198211000-00004