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Case Report: Catecholamine-Secreting Paraganglioma of Glomus Jugulare Region
A 43-year-old woman had clinical and biochemical evidence of a secreting paraganglioma of the glomus jugulare region. Catecholamine secretion was exacerbated during embolization of the tumor before surgery and resulted in a life-threatening vasomotor attack. Preoperatively, pharmacologic blockade of...
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Published in: | The American journal of the medical sciences 1989-01, Vol.297 (1), p.46-48 |
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container_title | The American journal of the medical sciences |
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creator | Kremer, Richard Michel, Rene P. Posner, Barry Wang, N.-S. Lafond, Guy P. Crawhall, John C. |
description | A 43-year-old woman had clinical and biochemical evidence of a secreting paraganglioma of the glomus jugulare region. Catecholamine secretion was exacerbated during embolization of the tumor before surgery and resulted in a life-threatening vasomotor attack. Preoperatively, pharmacologic blockade of excessive catecholamine secretion with prazocin controlled her blood pressure, tachycardia, and symptoms. The tumor was resected and its catecholamine content measured. This case is reported to stress the importance of adequate preoperative assessment of patients with paragangliomas of the head and neck. The extreme rarity of catecholamine-secreting tumors of this region should not lead us to underestimate the morbidity and mortality of such patients undergoing surgery or any other invasive procedure whether the diagnosis is confirmed or only suspected. |
doi_str_mv | 10.1097/00000441-198901000-00011 |
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Catecholamine secretion was exacerbated during embolization of the tumor before surgery and resulted in a life-threatening vasomotor attack. Preoperatively, pharmacologic blockade of excessive catecholamine secretion with prazocin controlled her blood pressure, tachycardia, and symptoms. The tumor was resected and its catecholamine content measured. This case is reported to stress the importance of adequate preoperative assessment of patients with paragangliomas of the head and neck. The extreme rarity of catecholamine-secreting tumors of this region should not lead us to underestimate the morbidity and mortality of such patients undergoing surgery or any other invasive procedure whether the diagnosis is confirmed or only suspected.</description><identifier>ISSN: 0002-9629</identifier><identifier>EISSN: 1538-2990</identifier><identifier>DOI: 10.1097/00000441-198901000-00011</identifier><identifier>CODEN: AJMSA9</identifier><language>eng</language><publisher>Hagerstown, MD: Elsevier Inc</publisher><subject>Biological and medical sciences ; Catecholamine ; Medical sciences ; Neurology ; Paraganglioma ; Tumors of the nervous system. 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Catecholamine secretion was exacerbated during embolization of the tumor before surgery and resulted in a life-threatening vasomotor attack. Preoperatively, pharmacologic blockade of excessive catecholamine secretion with prazocin controlled her blood pressure, tachycardia, and symptoms. The tumor was resected and its catecholamine content measured. This case is reported to stress the importance of adequate preoperative assessment of patients with paragangliomas of the head and neck. The extreme rarity of catecholamine-secreting tumors of this region should not lead us to underestimate the morbidity and mortality of such patients undergoing surgery or any other invasive procedure whether the diagnosis is confirmed or only suspected.</description><subject>Biological and medical sciences</subject><subject>Catecholamine</subject><subject>Medical sciences</subject><subject>Neurology</subject><subject>Paraganglioma</subject><subject>Tumors of the nervous system. 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Phacomatoses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kremer, Richard</creatorcontrib><creatorcontrib>Michel, Rene P.</creatorcontrib><creatorcontrib>Posner, Barry</creatorcontrib><creatorcontrib>Wang, N.-S.</creatorcontrib><creatorcontrib>Lafond, Guy P.</creatorcontrib><creatorcontrib>Crawhall, John C.</creatorcontrib><collection>Pascal-Francis</collection><collection>CrossRef</collection><jtitle>The American journal of the medical sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kremer, Richard</au><au>Michel, Rene P.</au><au>Posner, Barry</au><au>Wang, N.-S.</au><au>Lafond, Guy P.</au><au>Crawhall, John C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Case Report: Catecholamine-Secreting Paraganglioma of Glomus Jugulare Region</atitle><jtitle>The American journal of the medical sciences</jtitle><date>1989-01</date><risdate>1989</risdate><volume>297</volume><issue>1</issue><spage>46</spage><epage>48</epage><pages>46-48</pages><issn>0002-9629</issn><eissn>1538-2990</eissn><coden>AJMSA9</coden><abstract>A 43-year-old woman had clinical and biochemical evidence of a secreting paraganglioma of the glomus jugulare region. Catecholamine secretion was exacerbated during embolization of the tumor before surgery and resulted in a life-threatening vasomotor attack. Preoperatively, pharmacologic blockade of excessive catecholamine secretion with prazocin controlled her blood pressure, tachycardia, and symptoms. The tumor was resected and its catecholamine content measured. This case is reported to stress the importance of adequate preoperative assessment of patients with paragangliomas of the head and neck. The extreme rarity of catecholamine-secreting tumors of this region should not lead us to underestimate the morbidity and mortality of such patients undergoing surgery or any other invasive procedure whether the diagnosis is confirmed or only suspected.</abstract><cop>Hagerstown, MD</cop><pub>Elsevier Inc</pub><doi>10.1097/00000441-198901000-00011</doi><tpages>3</tpages></addata></record> |
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subjects | Biological and medical sciences Catecholamine Medical sciences Neurology Paraganglioma Tumors of the nervous system. Phacomatoses |
title | Case Report: Catecholamine-Secreting Paraganglioma of Glomus Jugulare Region |
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