Advances in Monoclonal Antibody Therapy of Cancer

Tumor-associated antigens can be seen as unique targets for the delivery of anticancer therapy. Monoclonal antibodies directed at such antigens are increasingly being seen as important biologic reagents that will complement the group of existing cytotoxic drugs. This report briefly overviews recent...

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Bibliographic Details
Published in:The American journal of the medical sciences 1992-09, Vol.304 (3), p.214-224
Main Authors: LoBuglio, Albert F., Saleh, Mansoor N.
Format: Article
Language:English
Subjects:
Animals
Antibodies, Monoclonal - genetics
Antibodies, Monoclonal - therapeutic use
Antineoplastic agents
Biological and medical sciences
Cancer
Female
Genetic Engineering
Humans
Immunotherapy
Immunotoxins - therapeutic use
Lymphoma - therapy
Medical sciences
Monoclonal antibody
Neoplasms - therapy
Pharmacology. Drug treatments
Radioimmunotherapy
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Summary:Tumor-associated antigens can be seen as unique targets for the delivery of anticancer therapy. Monoclonal antibodies directed at such antigens are increasingly being seen as important biologic reagents that will complement the group of existing cytotoxic drugs. This report briefly overviews recent advances in the field of monoclonal antibody therapy of cancer and provides insight regarding the promises and limitations of this novel therapeutic approach.
ISSN:0002-9629
1538-2990
DOI:10.1097/00000441-199209000-00011