The Calciuric Response to Dietary Salt of Dahl Salt-Sensitive and Salt-Resistant Male Rats

There are conflicting reports regarding the effect of salt sensitivity on the calciuric response to salt, perhaps because of gender differences and different modes of salt administration. We tested the hypothesis that the calciuric response to dietary salt would not differ for male Dahl salt-sensiti...

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Bibliographic Details
Published in:The American journal of the medical sciences 2001-05, Vol.321 (5), p.342-347
Main Authors: Thierry-Palmer, Myrtle, Sherman, Detrice D., Donkoh, Naana, Wang, Min, Bayorh, Mohamed A., Emmett, Nerimiah L.
Format: Article
Language:English
Subjects:
Analytical, structural and metabolic biochemistry
Animals
Arterial hypertension. Arterial hypotension
Biological and medical sciences
Blood and lymphatic vessels
Calcium - urine
Cardiology. Vascular system
Clinical manifestations. Epidemiology. Investigative techniques. Etiology
Fundamental and applied biological sciences. Psychology
Hypertension
Hypertension - chemically induced
Hypertension - metabolism
Inorganic compounds
Male
Medical sciences
Other biological molecules
Parathyroid hormone
Parathyroid Hormone - blood
Rats
Rats, Inbred Dahl
Salt sensitivity
Sodium - urine
Sodium chloride
Sodium, Dietary - pharmacology
Vitamin D
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Summary:There are conflicting reports regarding the effect of salt sensitivity on the calciuric response to salt, perhaps because of gender differences and different modes of salt administration. We tested the hypothesis that the calciuric response to dietary salt would not differ for male Dahl salt-sensitive (S) and salt-resistant (R) rats. S and R rats were fed high- (80g/kg) or low- (3g/kg) salt diets for 3 weeks and urine (24 hour) was collected weekly. Urinary calcium excretion was up to 20-fold greater for S and R rats fed a high-salt diet (P
ISSN:0002-9629
1538-2990
DOI:10.1097/00000441-200105000-00007