Life-Style Factors and Female Infertility

We summarize the epidemiologic literature on the effect of life-style factors such as cigarette smoking, alcohol and caffeine consumption, physical exercise, body mass index, and drug use on female infertility. We identified relevant papers through MEDLINE, Index Medicus, and a manual review of refe...

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Bibliographic Details
Published in:Epidemiology (Cambridge, Mass.) Mass.), 1997-07, Vol.8 (4), p.435-441
Main Authors: Buck, Germaine M., Sever, Lowell E., Batt, Ronald E., Mendola, Pauline
Format: Article
Language:English
Subjects:
Age distribution
Alcohol Drinking - adverse effects
Alcohol Drinking - epidemiology
Alcohols
Biological and medical sciences
Birth control
Body Weight
Caffeine - adverse effects
Cigarette smoking
Epidemiology
Fecundity
Female
Female infertility
Gynecology. Andrology. Obstetrics
Humans
Infertility, Female - classification
Infertility, Female - epidemiology
Infertility, Female - etiology
Intrauterine devices
Intrauterine Devices - adverse effects
Intrauterine Devices - utilization
Life Style
Logistic regression
Medical sciences
Patient Acceptance of Health Care
Predisposing factors
Pregnancy
Prevalence
Review
Risk Factors
Smoking - adverse effects
Smoking - epidemiology
Sterility. Assisted procreation
Substance-Related Disorders - complications
Substance-Related Disorders - epidemiology
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Summary:We summarize the epidemiologic literature on the effect of life-style factors such as cigarette smoking, alcohol and caffeine consumption, physical exercise, body mass index, and drug use on female infertility. We identified relevant papers through MEDLINE, Index Medicus, and a manual review of reference lists. Risk factors that affect the risk of primary tubal infertility and that were corroborated in two or more studies include use of intrauterine devices (especially the Dalkon Shield) and cigarette smoking. We identified extremes in body size as a risk factor for primary ovulatory infertility. Cocaine, marijuana and alcohol use, exercise, caffeine consumption, and ever-use of thyroid medications were possible risk factors for various subtypes of primary infertility. Few risk factors have been assessed or identified for secondary infertility or other less common subtypes, such as cervical or endometriosis-related infertility.
ISSN:1044-3983
1531-5487
DOI:10.1097/00001648-199707000-00015