Early Detection of Tuberous Sclerosis by l-123 IMP SPECT in a Neonate

The authors used l-123 IMP SPECT imaging to detect tuberous sclerosis in a neonate. Two hours after normal birth, the baby had a seizure. Electrocephalography revealed an abnormal wave on the left temporal lobe. On the eighth day after the birth, brain SPECT Imaging was performed using N-isopropyl l...

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Bibliographic Details
Published in:Clinical nuclear medicine 1994-09, Vol.19 (9), p.824-824
Main Authors: OSHIMA, MOTOO, YASUKOCHI, HIROSHI
Format: Article
Language:English
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Summary:The authors used l-123 IMP SPECT imaging to detect tuberous sclerosis in a neonate. Two hours after normal birth, the baby had a seizure. Electrocephalography revealed an abnormal wave on the left temporal lobe. On the eighth day after the birth, brain SPECT Imaging was performed using N-isopropyl lodoamphetamine (l-123 IMP). The brain SPECT image showed marked uptake in the left fronto-temporal lobe, corresponding to the high-density area noted on computed tomography. One year later, l-123 IMP SPECT showed hypoperfusion corresponding to the calcified lesion seen on the CT scan. After surgical resection, this lesion was histologically proven to be tuberous sclerosis.
ISSN:0363-9762
1536-0229
DOI:10.1097/00003072-199409000-00020