Testicular I-131 6β-Iodomethyl-19-Norcholesterol Uptake in a Patient With Adrenogenital Syndrome

A 38-year-old man with congenital adrenal hyperplasia, salt losing variety, on a maintenance dose of 25 mg of cortisone acetate daily, presented with decreased libido and premature ejaculation, but no other constitutional symptoms. He was noted to have bilateral testicular masses. Ultrasound showed...

Full description

Saved in:
Bibliographic Details
Published in:Clinical nuclear medicine 1999-06, Vol.24 (6), p.464-464
Main Authors: ASSI, ZAKARIA I, BOHNEN, NICOLAAS I, SCHTEINGART, DAVID E, GROSS, MILTON D, SHAPIRO, BRAHM
Format: Article
Language:English
Subjects:
Biological and medical sciences
Endocrine glands. Genital system. Mammary gland
Gynecology. Andrology. Obstetrics
Investigative techniques, diagnostic techniques (general aspects)
Male genital diseases
Medical sciences
Radionuclide investigations
Tumors
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A 38-year-old man with congenital adrenal hyperplasia, salt losing variety, on a maintenance dose of 25 mg of cortisone acetate daily, presented with decreased libido and premature ejaculation, but no other constitutional symptoms. He was noted to have bilateral testicular masses. Ultrasound showed infiltrative tumors in both testicles. Laboratory testing revealed an elevated ACTH of 500 pg/ml (normal range 9-52 pg/ml) reflecting inadequate corticosteroid replacement. A I-131 6β-Iodomethyl-19-Norcholesterol (NP-59) scan demonstrated prominent testicular uptake indicating the steroid producing nature of the testicular masses.
ISSN:0363-9762
1536-0229
DOI:10.1097/00003072-199906000-00026