In Vitro Evaluations of Condoms with and Without Nonoxynol 9 As Physical and Chemical Barriers Against Chlamydia Trachomatis, Herpes Simplex Virus Type 2, and Human Immunodeficiency Virus

Simulated in vitro intercourse conditions demonstrated that unlubricated latex condoms provide an effective physical barrier to high concentrations of Chlamydia trachomatis, herpes simplex virus type 2, and human immunodeficiency virus. However, since condoms can be damaged after manufacturing inspe...

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Bibliographic Details
Published in:Sexually transmitted diseases 1989-04, Vol.16 (2), p.51-56
Main Authors: JUDSON, FRANKLYN N., EHRET, JOSEPHINE M., BODIN, GUY F., LEVIN, MYRON J., RIETMEIJER, CORNELIS A. M.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Chlamydia trachomatis - drug effects
Contraceptive Devices, Male
Evaluation Studies as Topic
General aspects
HIV - drug effects
Human infectious diseases. Experimental studies and models
Humans
Infectious diseases
Latex
Medical sciences
Nonoxynol
Original Articles
Polyethylene Glycols - pharmacology
Simplexvirus - drug effects
Spermatocidal Agents - pharmacology
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Summary:Simulated in vitro intercourse conditions demonstrated that unlubricated latex condoms provide an effective physical barrier to high concentrations of Chlamydia trachomatis, herpes simplex virus type 2, and human immunodeficiency virus. However, since condoms can be damaged after manufacturing inspection and prior to use, latex condoms alone should not be perceived as absolute protection against STDs. Nonoxynol 9 used in conjunction with condoms provided additional, yet still not foolproof, protection against the three viruses.
ISSN:0148-5717
1537-4521
DOI:10.1097/00007435-198904000-00001