Complications from injectable polyacrylamide gel, a new nonbiodegradable soft tissue filler

Polyacrylamide gels, containing a hydrogel composed of polyacrylamide and water, are used for soft tissue augmentation and contour correction. There are no reports of significant complications after injection of this material into the face. We report an inflammatory reaction after injection of polya...

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Bibliographic Details
Published in:Dermatologic surgery 2004-12, Vol.30 (12), p.1507-1509
Main Authors: AMIN, Snehal P, MARMUR, Ellen S, GOLDBERG, David J
Format: Article
Language:English
Subjects:
Acrylic Resins - administration & dosage
Acrylic Resins - adverse effects
Biological and medical sciences
Cosmetic Techniques - adverse effects
Dermatology
Diagnosis, Differential
Face
Female
Foreign-Body Reaction - diagnosis
Foreign-Body Reaction - etiology
Foreign-Body Reaction - pathology
Gels - adverse effects
Humans
Injections - adverse effects
Medical sciences
Middle Aged
Prostheses and Implants - adverse effects
Skin plastic surgery
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Zygoma
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Summary:Polyacrylamide gels, containing a hydrogel composed of polyacrylamide and water, are used for soft tissue augmentation and contour correction. There are no reports of significant complications after injection of this material into the face. We report an inflammatory reaction after injection of polyacrylamide gels for zygomatic facial augmentation. A retrospective chart review of single case is presented. An inflammatory reaction at the sites of polyacrylamide gels injection was noted at 1 month after initial injection. Despite two ensuing courses of broad-spectrum antibiotics, the patient presented to us with persistent draining nodules. Intralesional steroid injections resulted in prompt resolution and no recurrence. Inflammatory reactions have been noted in patients receiving polyacrylamide gels for breast augmentation. Facial polyacrylamide gels injections may also be associated with an inflammatory reaction that responds to intralesional steroids. With increasing availability of a variety of soft tissue fillers, dermatologists should be aware of this delayed complication from polyacrylamide gels.
ISSN:1076-0512
1524-4725
DOI:10.1097/00042728-200412020-00001