Cardiovascular Responses to Physical and Psychological Stress in Female Alcoholics With Transitory Hypertension After Early Abstinence

Background: Male alcoholic patients with acute withdrawal hypertension have shown exaggerated cardiovascular reactivity to stress after 3 to 4 weeks of abstinence, although resting blood pressures (BP) had returned to normal. Studies of this nature, however, have not been extended to women. Methods:...

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Bibliographic Details
Published in:Alcoholism, clinical and experimental research clinical and experimental research, 2003-09, Vol.27 (9), p.1489-1498
Main Authors: Bernardy, Nancy C., King, Andrea C., Lovallo, William R.
Format: Article
Language:English
Subjects:
Adult
Alcohol Dependence
Alcoholism - physiopathology
Alcoholism - rehabilitation
Alcoholism and acute alcohol poisoning
Arousal - drug effects
Arousal - physiology
Biological and medical sciences
Blood Pressure
Cardiovascular Reactivity
Ethanol - adverse effects
Female
Follow-Up Studies
Hand Strength - physiology
Humans
Hypertension - physiopathology
Isometric Contraction - physiology
Medical sciences
Middle Aged
Patient Admission
Reference Values
Remission, Spontaneous
Sex Factors
Speech
Stress
Stress, Physiological - complications
Stress, Physiological - physiopathology
Stress, Psychological - complications
Stress, Psychological - physiopathology
Substance Abuse Treatment Centers
Substance Withdrawal Syndrome - physiopathology
Substance Withdrawal Syndrome - rehabilitation
Temperance
Toxicology
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Summary:Background: Male alcoholic patients with acute withdrawal hypertension have shown exaggerated cardiovascular reactivity to stress after 3 to 4 weeks of abstinence, although resting blood pressures (BP) had returned to normal. Studies of this nature, however, have not been extended to women. Methods: In this study, 32 alcohol‐dependent women, abstinent for 4 weeks, were compared with 16 healthy controls on cardiovascular hemodynamics during rest and in response to 2 moderately aversive stressors: isometric handgrip and a speech task. The alcoholics were placed according to withdrawal BP into transitory hypertensive (tHT; n= 16; BP ≥140/90 mm Hg) and normotensive (NT; n= 16; BP
ISSN:0145-6008
1530-0277
DOI:10.1097/01.ALC.0000085587.00498.38