PB2287 REFERENCE INTERVALS OF BLOOD COUNT IN HEALTHY FULL‐TERM PREGNANT GREEK WOMEN

• Published in: HemaSphere 2019-06, Vol.3 (S1), p.1021-1022
• Main Authors: Karantani, K., Petassis, G., Tsioni, K., Issa, M., Tsamis, E., Vagdatli, E.
• Format: Article
• Language: English
• ISSN: 2572-9241; 2572-9241
• DOI: 10.1097/01.HS9.0000567616.62889.31

Background: Since blood count reference intervals are generally based on samples collected from non pregnant women, these should not be used for the evaluation of pregnant women. Aims: The aim of this study was to determine White Blood Cells (WBC), Neutrophils (NEU) and Lymphocytes (LY) reference ranges in healthy Greek full‐term pregnant women and to evaluate them before and after delivery. Methods: Blood samples from 278 healthy pregnant women, before and after labour were collected using EDTA anticoagulated tubes. WBC, NEU and LY were determined in COULTER LH780 analyzer pre and one or two days post partum. 5% of the upper and lower results concerning WBC, NEU and LY were excluded. A normality test was performed using SPSS 21 statistical software and median, minimum and maximum ranges were calculated. Results: The WBC, NEU and LY mean, median, maximum and minimum values in healthy prepartum women are showed in Table I. Out of 278 pregnant women, only in 112 (40,3%), there was a statistically significant (p = 0.001) decrease in WBC post partum with a simultaneous fall of NEU in 84,8% of them. Furthermore, there was a post partum NEU decrease, only in 129 (46,4%) out of them, albeit not statistically significant (p = 0.283), whereas there was a LY significant fall (p = 0.004) in 114 (41,64%) of them. Summary/Conclusion: WBC and NEU in healthy full term pregnant women prepartum are elevated, while LY are within normal range.40,3% reduce WBC post partum. Nevertheless, in an excessive number women post partum develop elevated WBC due to possible infection.