Radiation-Induced Meningioma in a Case of Medulloblastoma Treated 11 Years Ago—Detected on 68Ga-DOTANOC PET/CT

Medulloblastomas, especially the sonic hedgehog subgroup, are treated aggressively with surgery and chemoradiotherapy, as they are associated with high local site recurrence rate and poor overall survival. Radiation-induced meningioma is the most common delayed complication of craniospinal irradiati...

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Bibliographic Details
Published in:Clinical nuclear medicine 2022-01, Vol.47 (1), p.e108-e110
Main Authors: Dev, Indraja D., Puranik, Ameya D., Rangarajan, Venkatesh, Gupta, Tejpal, Purandare, Nilendu C., Agrawal, Archi, Shah, Sneha
Format: Article
Language:English
Subjects:
Cerebellar Neoplasms - radiotherapy
Humans
Medulloblastoma - radiotherapy
Meningioma - diagnostic imaging
Neoplasms, Radiation-Induced - diagnostic imaging
Organometallic Compounds
Positron Emission Tomography Computed Tomography
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Summary:Medulloblastomas, especially the sonic hedgehog subgroup, are treated aggressively with surgery and chemoradiotherapy, as they are associated with high local site recurrence rate and poor overall survival. Radiation-induced meningioma is the most common delayed complication of craniospinal irradiation. This needs to be differentiated from meningeal or ependymal metastases as the later need aggressive management. We report one such rare case, in a patient who completed treatment for medulloblastoma 11 years ago, was in remission, and now presented with dural-based lesions.
ISSN:0363-9762
1536-0229
DOI:10.1097/RLU.0000000000003788