18F-FDG and 68Ga-FAPI-04 PET/CT Imaging of a Case With Immunoglobulin G4–Related Disease Presenting as Hepatic Masses

Two hepatic masses were discovered through ultrasonography in a 50-year-old man with increased CA19-9, which is highly suspicious for malignancy. PET/CT images revealed intense 18 F-FDG and 68 Ga-FAPI-04 uptake in intrahepatic lesions. Histopathology with biopsy confirmed the diagnosis of immunoglob...

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Bibliographic Details
Published in:Clinical nuclear medicine 2022-12, Vol.47 (12), p.1092-1094
Main Authors: Zhang, Zeyu, Jiang, Hui, Zhang, Lu, Cheng, Chao, Zuo, Changjing
Format: Article
Language:English
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Summary:Two hepatic masses were discovered through ultrasonography in a 50-year-old man with increased CA19-9, which is highly suspicious for malignancy. PET/CT images revealed intense 18 F-FDG and 68 Ga-FAPI-04 uptake in intrahepatic lesions. Histopathology with biopsy confirmed the diagnosis of immunoglobulin G4 (IgG4)–related disease. Here, we reported a case of IgG4-related primary localized pseudotumor without any other organ involvement. We concluded that in clinical work, if intrahepatic masses show high uptake of 18 F-FDG or 68 Ga-FAPI-04, intrahepatic IgG4-related disease should be considered for differential diagnosis.
ISSN:0363-9762
1536-0229
DOI:10.1097/RLU.0000000000004377