68Ga-DOTA-FAPI-04 PET/CT Imaging in a Case of Radioactive Iodine–Induced Chronic Parotitis

68Ga-DOTA-FAPI-04 is a promising PET agent for tumor imaging. However, inflammatory lesions can also show increased FAPI uptake. Herein, we reported a 52-year-old woman who underwent total thyroidectomy for thyroid papillary carcinoma 1 year ago and underwent adjuvant radioiodine therapy 1 month lat...

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Bibliographic Details
Published in:Clinical nuclear medicine 2022-12, Vol.47 (12), p.1082-1083
Main Authors: Xu, Tingting, Zhang, Yan, Wu, Ruilin, Ding, Haoyuan, Chen, Yue
Format: Article
Language:English
Subjects:
Female
Humans
Iodine Radioisotopes - adverse effects
Middle Aged
Parotitis
Positron Emission Tomography Computed Tomography - methods
Thyroid Neoplasms - diagnostic imaging
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Summary:68Ga-DOTA-FAPI-04 is a promising PET agent for tumor imaging. However, inflammatory lesions can also show increased FAPI uptake. Herein, we reported a 52-year-old woman who underwent total thyroidectomy for thyroid papillary carcinoma 1 year ago and underwent adjuvant radioiodine therapy 1 month later. After 131I therapy, she began to develop pain and swelling in bilateral cheeks, which developed into oral dryness. The patient was diagnosed with radioactive iodine-induced parotitis. 68Ga-DOTA-FAPI-04 PET/CT showed the density of bilateral parotid glands increased, and the volume decreased with intense tracer uptake. 99mTcO4- salivary gland scintigraphy showed decreased tracer uptake in the bilateral parotid glands.
ISSN:0363-9762
1536-0229
DOI:10.1097/RLU.0000000000004416