Syphilis Mimicking Malignant Pulmonary Tumor With Nodal and Bone Metastasis on 18F-FDG PET/CT

A 52-year-old man suffering left pleuritic pain underwent a chest CT showing a subpleural pulmonary nodule in the left upper lobe. Because of the possibility of a lung tumor, he was referred for 18 F-FDG PET/CT. The scan revealed FDG uptake in the pulmonary nodule, in an upper right paratracheal lym...

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Bibliographic Details
Published in:Clinical nuclear medicine 2023-11, Vol.48 (11), p.e526-e528
Main Authors: Bronte Viedma, Angela, Menendez-Sanchez, Sandra, Bastidas Tamayo, Juan Fernando, Lajusticia Andrés, Héctor, García-Velloso, Maria José
Format: Article
Language:English
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Summary:A 52-year-old man suffering left pleuritic pain underwent a chest CT showing a subpleural pulmonary nodule in the left upper lobe. Because of the possibility of a lung tumor, he was referred for 18 F-FDG PET/CT. The scan revealed FDG uptake in the pulmonary nodule, in an upper right paratracheal lymph node, and at 4 destructive bone lesions. Pathologic examination after pulmonary biopsy manifested only the presence of inflammatory cells. Further clinical history research proved risky sexual behavior with a positive syphilis serology test. A follow-up PET/CT 7 months after penicillin therapy showed a complete metabolic response of all the lesions.
ISSN:0363-9762
1536-0229
DOI:10.1097/RLU.0000000000004836