Extensive Pulmonary AL Amyloidosis Mimicking Miliary Tuberculosis: The Diagnostic Utility of 99mTc-PYP Scintigraphy

Amyloidosis is a misfolded protein deposition disorder within the extracellular matrix, leading to dysfunction in the affected organ. Primary amyloidosis manifests as AL and ATTR subtypes, wherein AL is associated with plasma cell dyscrasias. Herein we present a case of a patient who underwent inves...

Full description

Saved in:
Bibliographic Details
Published in:Clinical nuclear medicine 2024-11, Vol.49 (11), p.e608-e609
Main Authors: Denizmen, Dilara, Isik, Emine Goknur, Vuralli Bakkaloglu, Dogu, Buyukkaya, Fikret, Sanli, Yasemin
Format: Article
Language:English
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Amyloidosis is a misfolded protein deposition disorder within the extracellular matrix, leading to dysfunction in the affected organ. Primary amyloidosis manifests as AL and ATTR subtypes, wherein AL is associated with plasma cell dyscrasias. Herein we present a case of a patient who underwent investigation due to the presence of bilateral reticulonodular lung infiltrates, suggestive of miliary tuberculosis. 99m Tc-PYP scan revealed widespread radiotracer uptake in the lungs leading to diagnosis of AL amyloidosis.
ISSN:0363-9762
1536-0229
DOI:10.1097/RLU.0000000000005442