(2 R ,4 R )-4-(2-Ethoxy-2-oxoethyl)-2,6,6-trimethyl–2-oxo-1,3,6,2λ 5 -dioxazaphosphocan-6-ium iodide

• Published in: Acta crystallographica. Section E, Structure reports online Structure reports online, 2012-06, Vol.68 (6), p.o1596-o1596
• Main Authors: Fulfer, Bradford W., Fronczek, Frank R., Watkins, Steven F.
• Format: Article
• Language: English
• ISSN: 1600-5368; 1600-5368
• DOI: 10.1107/S1600536812018466

The title compound, C 11 H 23 NO 5 P + ·I − , consists of an eight-membered cationic heterocyclic ring in a boat–chair conformation. The ring features a tetraalkylammonium N and a methylphosphonate P atom. A –CH 2 (CO)OC 2 H 5 ester side chain at the C adjacent to oxygen produces two chiral centers at that substituted C atom and the P atom, both of which were determined to have absolute R , R configurations. A previously determined racemic bromide analog has exactly the same ring but with a –C 15 H 31 side chain. In that structure, both chiral centers show the same relative R / S , R / S configurations, but the ring in the bromide analog is in a boat conformation.