Picosecond electronic time-gated imaging of bones in tissues

Two-dimensional in vivo optical images of metacarpal bones of a human palm and in vitro images of turkey and chicken bones embedded in tissues were obtained in the near-infrared region using femtosecond pulse transillumination and picosecond electronic time-sliced detection technique. A small hole d...

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Bibliographic Details
Published in:IEEE journal of selected topics in quantum electronics 1999-07, Vol.5 (4), p.916-922
Main Authors: Zevallos, M.E., Gayen, S.K., Baran Das, B., Alrubaiee, M., Alfano, R.R.
Format: Article
Language:English
Subjects:
Bone
Bone diseases
Bones
Breast
Breast tissue
Chickens
Diseases
Electronics
Fluorescence
Humans
Imaging
In vitro
In vivo
Laser diagnostics
Laser tissue interaction
Light scattering
Medical imaging
Optical imaging
Optical pulses
Palm
Ultrafast electronics
Ultrafast optics
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Description
Summary:Two-dimensional in vivo optical images of metacarpal bones of a human palm and in vitro images of turkey and chicken bones embedded in tissues were obtained in the near-infrared region using femtosecond pulse transillumination and picosecond electronic time-sliced detection technique. A small hole drilled in chicken bone and embedded in chicken breast tissue was imaged using early arriving light. Time-gated fluorescence images of an interior marrow region of a bone injected with a fluorescent dye were recorded. The techniques have potential for monitoring bone fracture, bone diseases such as, osteoporosis and arthritis, and diseases that originate in or affect bone marrow.
ISSN:1077-260X
1558-4542
DOI:10.1109/2944.796311