A 3-Step Process to Estimate Phenylalanine in Commercial Foods for PKU Management

Phenylalanine (Phe) is a key nutrient in the dietary management of the metabolic disease phenylketonuria (PKU). To give more freedom to PKU patients, we propose a numerical process to estimate the Phe content of a commercial food using the information printed on the label (Nutritional Fact Label and...

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Bibliographic Details
Published in:IEEE access 2018, Vol.6, p.30758-30765
Main Authors: Kim, Jieun, Talikoti, Amruthavarshini, Boutin, Mireille
Format: Article
Language:English
Subjects:
Amino acids
Applications programs
Diseases
Estimation
Food
Food analysis
medical diet
Metabolic disorders
mobile health
Nutrients
Optimization
Phenylalanine
Phenylketonuria
PKU
Proteins
Smart phones
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Summary:Phenylalanine (Phe) is a key nutrient in the dietary management of the metabolic disease phenylketonuria (PKU). To give more freedom to PKU patients, we propose a numerical process to estimate the Phe content of a commercial food using the information printed on the label (Nutritional Fact Label and ordered ingredient list). The process is amenable to implementation as a smart phone/Web app and could be integrated into a personalized dietary management software. Our tests show that the results are very accurate (±13 mg per serving) in the vast majority of foods considered. Our approach can be modified to handle any other amino acid for the management of other inborn errors of metabolism. A similar approach can also be used for improving the precision (i.e., increasing the quantization resolution) of the nutrients already listed (e.g., protein).
ISSN:2169-3536
2169-3536
DOI:10.1109/ACCESS.2018.2839079