Low-Voltage, Low-Area, nW-Power CMOS Digital-Based Biosignal Amplifier

This paper presents the operation principle and the silicon characterization of a power efficient ultra-low voltage and ultra-low area fully-differential, digital-based Operational Transconductance Amplifier (OTA), suitable for microscale biosensing applications (BioDIGOTA). Measured results in 180n...

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Bibliographic Details
Published in:IEEE access 2022, Vol.10, p.44106-44115
Main Authors: Toledo, Pedro, Crovetti, Paolo S., Klimach, Hamilton D., Musolino, Francesco, Bampi, Sergio
Format: Article
Language:English
Subjects:
Biosensors
CMOS
digital-based circuit
Inverters
Logic gates
Low voltage
Operational amplifiers
operational transconductance amplifier (OTA)
Oscillators
Silicon
Symbols
the Internet of Things (IoT)
Transconductance
ultra-low power (ULP)
Ultra-low voltage (ULV) CMOS
Voltage
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Summary:This paper presents the operation principle and the silicon characterization of a power efficient ultra-low voltage and ultra-low area fully-differential, digital-based Operational Transconductance Amplifier (OTA), suitable for microscale biosensing applications (BioDIGOTA). Measured results in 180nm CMOS prototypes show that the proposed BioDIGOTA is able to work with a supply voltage down to 400 mV, consuming only 95 nW. Owing to its intrinsically highly-digital feature, the BioDIGOTA layout occupies only 0.022 mm 2 of total silicon area, lowering the area by 3.22\times times compared to the current state of the art, while keeping reasonable system performance, such as 7.6 NEF with 1.25~\mu V_{\mathrm {RMS}} input referred noise over a 10 Hz bandwidth, 1.8% of THD, 62 dB of CMRR and 55 dB of PSRR.
ISSN:2169-3536
2169-3536
DOI:10.1109/ACCESS.2022.3168603