Experimental Evaluation of a 3-D CZT Imaging Spectrometer for Potential Use in Compton-Enhanced PET Imaging

We constructed a prototype positron emission tomography (PET) system and experimentally evaluated large-volume 3-D cadmium zinc telluride (CZT) detectors for potential use in Compton-enhanced PET imaging. The CZT spectrometer offers sub-0.5 mm spatial resolution, an ultrahigh energy resolution ( 1%...

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Bibliographic Details
Published in:IEEE transactions on radiation and plasma medical sciences 2023-01, Vol.7 (1), p.1-1
Main Authors: Jin, Yifei, Streicher, Michael, Yang, Hao, Brown, Steven, He, Zhong, Meng, Ling-Jian
Format: Article
Language:English
Subjects:
Cadmium
Cadmium zinc tellurides
Compton scattering
CZT detector
Detectors
Emission analysis
Energy resolution
Gamma rays
Image enhancement
Image quality
Image resolution
Imaging
Imaging spectrometers
Kinematics
Numerical integration
Panels
PET
Photons
Point sources
Positron emission
Positron emission tomography
Prototypes
Sensors
Spatial discrimination
Spatial resolution
Zinc telluride
Zinc tellurides
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Summary:We constructed a prototype positron emission tomography (PET) system and experimentally evaluated large-volume 3-D cadmium zinc telluride (CZT) detectors for potential use in Compton-enhanced PET imaging. The CZT spectrometer offers sub-0.5 mm spatial resolution, an ultrahigh energy resolution ( 1% @ 511 keV) and the capability of detecting multiple gamma-ray interactions that simultaneously occurred. The system consists of four CZT detector panels with a detection area of around 4.4 cm × 4.4 cm. The distance between the front surfaces of the two opposite CZT detector panels is 80 mm. This system allows us to detect coincident annihilation photons and Compton interactions inside the detectors and then exploit Compton kinematics to predict the first Compton interaction site and reject chance coincidences. We have developed a numerical integration technique to model the near-field Compton response that incorporates Doppler broadening, detector's finite resolutions, and the distance between the first and second interactions. This method was used to effectively reject random and scattered coincidence events. In the preliminary imaging studies, we have used point-sources, line-sources, a custom-designed resolution phantom and a commercial image quality (IQ) phantom to demonstrate an imaging resolution of approximately 0.75 mm in PET images, and Compton-based enhancement.
ISSN:2469-7311
2469-7303
DOI:10.1109/TRPMS.2022.3200010