The association between tricuspid regurgitation velocity and 5‐year survival in a N orth W est L ondon population of patients with sickle cell disease in the U nited K ingdom

Raised tricuspid regurgitant velocity ( TRV ) occurs in approximately 30% of adults with sickle cell disease ( SCD ), and has been shown to be an independent risk factor for death. TRV was assessed in 164 SCD patients who were subsequently followed up for survival. Raised pulmonary pressures were de...

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Published in:British journal of haematology 2013-08, Vol.162 (3), p.400-408
Main Authors: Zimbarra Cabrita, Inês, Mohammed, Abubakar, Layton, Mark, Ghorashian, Sara, Gilmore, Annette, Cho, Gavin, Howard, Jo, Anie, Kofi A., Desforges, Lynda, Bassett, Paul, Grapsa, Julia, Howard, Luke, Mahalingam, Gaia, Dawson, David, Pinto, Fausto J., Nihoyannopoulos, Petros, Davies, Sally C., Gibbs, J. Simon R.
Format: Article
Language:English
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Summary:Raised tricuspid regurgitant velocity ( TRV ) occurs in approximately 30% of adults with sickle cell disease ( SCD ), and has been shown to be an independent risk factor for death. TRV was assessed in 164 SCD patients who were subsequently followed up for survival. Raised pulmonary pressures were defined as a TRV jet ≥2·5 m/s on echocardiography. Elevated TRV was present in 29·1% of patients and it was associated with increased age and left atrial diameter. There were 15 deaths (9·1%) over a median of 68·1 months follow up; seven patients had increased TRV , and eight patients had a TRV
ISSN:0007-1048
1365-2141
DOI:10.1111/bjh.12391