Effect of vitamin D on blood–brain barrier function in multiple sclerosis

Vitamin D deficiency might be a risk factor for multiple sclerosis ( MS ). The active form of vitamin D has some protective effects on MS . The study by Takahashi et al. in this issue addressed the question of how vitamin D works on MS pathology. Using a human brain microvascular endothelial cell li...

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Bibliographic Details
Published in:Clinical & experimental neuroimmunology 2017-08, Vol.8 (3), p.180-180
Main Author: Suzumura, Akio
Format: Article
Language:English
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Summary:Vitamin D deficiency might be a risk factor for multiple sclerosis ( MS ). The active form of vitamin D has some protective effects on MS . The study by Takahashi et al. in this issue addressed the question of how vitamin D works on MS pathology. Using a human brain microvascular endothelial cell line, they showed that vitamin D attenuated the damage of barrier function of the cell line after exposure to either MS sera or tumor necrosis factor‐α. The study along with their previous study suggests that vitamin D might protect blood–brain barrier function, and could give us a rationale for the use of vitamin D in MS patients. This is commentary to introduce the paper showing that vitamin D attenuates the damage of blood‐brain barrier function.
ISSN:1759-1961
1759-1961
DOI:10.1111/cen3.12410