Fatal hepatocellular carcinoma presenting with oral metastasis in a patient with synchronic primary malignancies of prostate and liver

Background Hepatocellular carcinoma (HCC) is the most frequent type of liver cancer and its occurrence in the oral cavity as a metastatic neoplasm is a rare event. We describe a fatal case of HCC with oral metastasis in a patient firstly diagnosed with prostatic and hepatic carcinomas. The histopath...

Full description

Saved in:
Bibliographic Details
Published in:Gerodontology 2017-06, Vol.34 (2), p.272-275
Main Authors: Rodrigues, Maria Fernanda Setúbal Destro, Esteves, Carina Magalhães, Oliveira, Márcio Augusto, Andrade, Nathália Paiva, Sedassari, Bruno Tavares, Soares, Fernando Augusto, Nunes, Fabio Daumas
Format: Article
Language:English
Subjects:
Aged
Carcinoma, Hepatocellular - secondary
Fatal Outcome
hepatocellular carcinoma
Humans
immunohistochemistry
Liver Neoplasms - pathology
Male
Mouth Mucosa - pathology
Mouth Neoplasms - secondary
Neoplasms, Second Primary - pathology
oral metastasis
Prostatic Neoplasms - pathology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background Hepatocellular carcinoma (HCC) is the most frequent type of liver cancer and its occurrence in the oral cavity as a metastatic neoplasm is a rare event. We describe a fatal case of HCC with oral metastasis in a patient firstly diagnosed with prostatic and hepatic carcinomas. The histopathological examination revealed a hepatocyte‐like tumour cells arranged in organoid structures as well as positivity to cytokeratin 8 and Hep Par 1. The present findings highlight the importance of a complete medical evaluation of the patient to identify possible oral repercussions of primary diseases.
ISSN:0734-0664
1741-2358
DOI:10.1111/ger.12236