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Fatal hepatocellular carcinoma presenting with oral metastasis in a patient with synchronic primary malignancies of prostate and liver

Background Hepatocellular carcinoma (HCC) is the most frequent type of liver cancer and its occurrence in the oral cavity as a metastatic neoplasm is a rare event. We describe a fatal case of HCC with oral metastasis in a patient firstly diagnosed with prostatic and hepatic carcinomas. The histopath...

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Published in:Gerodontology 2017-06, Vol.34 (2), p.272-275
Main Authors: Rodrigues, Maria Fernanda Setúbal Destro, Esteves, Carina Magalhães, Oliveira, Márcio Augusto, Andrade, Nathália Paiva, Sedassari, Bruno Tavares, Soares, Fernando Augusto, Nunes, Fabio Daumas
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cited_by cdi_FETCH-LOGICAL-c2926-d48f94b08510ef431c87ea74b3777ceb449a9e2c77196b07014eabcfc6c694d23
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container_title Gerodontology
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creator Rodrigues, Maria Fernanda Setúbal Destro
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description Background Hepatocellular carcinoma (HCC) is the most frequent type of liver cancer and its occurrence in the oral cavity as a metastatic neoplasm is a rare event. We describe a fatal case of HCC with oral metastasis in a patient firstly diagnosed with prostatic and hepatic carcinomas. The histopathological examination revealed a hepatocyte‐like tumour cells arranged in organoid structures as well as positivity to cytokeratin 8 and Hep Par 1. The present findings highlight the importance of a complete medical evaluation of the patient to identify possible oral repercussions of primary diseases.
doi_str_mv 10.1111/ger.12236
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subjects Aged
Carcinoma, Hepatocellular - secondary
Fatal Outcome
hepatocellular carcinoma
Humans
immunohistochemistry
Liver Neoplasms - pathology
Male
Mouth Mucosa - pathology
Mouth Neoplasms - secondary
Neoplasms, Second Primary - pathology
oral metastasis
Prostatic Neoplasms - pathology
title Fatal hepatocellular carcinoma presenting with oral metastasis in a patient with synchronic primary malignancies of prostate and liver
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