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Fatal hepatocellular carcinoma presenting with oral metastasis in a patient with synchronic primary malignancies of prostate and liver
Background Hepatocellular carcinoma (HCC) is the most frequent type of liver cancer and its occurrence in the oral cavity as a metastatic neoplasm is a rare event. We describe a fatal case of HCC with oral metastasis in a patient firstly diagnosed with prostatic and hepatic carcinomas. The histopath...
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Published in: | Gerodontology 2017-06, Vol.34 (2), p.272-275 |
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container_end_page | 275 |
container_issue | 2 |
container_start_page | 272 |
container_title | Gerodontology |
container_volume | 34 |
creator | Rodrigues, Maria Fernanda Setúbal Destro Esteves, Carina Magalhães Oliveira, Márcio Augusto Andrade, Nathália Paiva Sedassari, Bruno Tavares Soares, Fernando Augusto Nunes, Fabio Daumas |
description | Background
Hepatocellular carcinoma (HCC) is the most frequent type of liver cancer and its occurrence in the oral cavity as a metastatic neoplasm is a rare event. We describe a fatal case of HCC with oral metastasis in a patient firstly diagnosed with prostatic and hepatic carcinomas. The histopathological examination revealed a hepatocyte‐like tumour cells arranged in organoid structures as well as positivity to cytokeratin 8 and Hep Par 1. The present findings highlight the importance of a complete medical evaluation of the patient to identify possible oral repercussions of primary diseases. |
doi_str_mv | 10.1111/ger.12236 |
format | article |
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Hepatocellular carcinoma (HCC) is the most frequent type of liver cancer and its occurrence in the oral cavity as a metastatic neoplasm is a rare event. We describe a fatal case of HCC with oral metastasis in a patient firstly diagnosed with prostatic and hepatic carcinomas. The histopathological examination revealed a hepatocyte‐like tumour cells arranged in organoid structures as well as positivity to cytokeratin 8 and Hep Par 1. The present findings highlight the importance of a complete medical evaluation of the patient to identify possible oral repercussions of primary diseases.</description><identifier>ISSN: 0734-0664</identifier><identifier>EISSN: 1741-2358</identifier><identifier>DOI: 10.1111/ger.12236</identifier><identifier>PMID: 27207742</identifier><language>eng</language><publisher>England</publisher><subject>Aged ; Carcinoma, Hepatocellular - secondary ; Fatal Outcome ; hepatocellular carcinoma ; Humans ; immunohistochemistry ; Liver Neoplasms - pathology ; Male ; Mouth Mucosa - pathology ; Mouth Neoplasms - secondary ; Neoplasms, Second Primary - pathology ; oral metastasis ; Prostatic Neoplasms - pathology</subject><ispartof>Gerodontology, 2017-06, Vol.34 (2), p.272-275</ispartof><rights>2016 John Wiley & Sons A/S and The Gerodontology Association. Published by John Wiley & Sons Ltd</rights><rights>2016 John Wiley & Sons A/S and The Gerodontology Association. Published by John Wiley & Sons Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2926-d48f94b08510ef431c87ea74b3777ceb449a9e2c77196b07014eabcfc6c694d23</citedby><cites>FETCH-LOGICAL-c2926-d48f94b08510ef431c87ea74b3777ceb449a9e2c77196b07014eabcfc6c694d23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27207742$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rodrigues, Maria Fernanda Setúbal Destro</creatorcontrib><creatorcontrib>Esteves, Carina Magalhães</creatorcontrib><creatorcontrib>Oliveira, Márcio Augusto</creatorcontrib><creatorcontrib>Andrade, Nathália Paiva</creatorcontrib><creatorcontrib>Sedassari, Bruno Tavares</creatorcontrib><creatorcontrib>Soares, Fernando Augusto</creatorcontrib><creatorcontrib>Nunes, Fabio Daumas</creatorcontrib><title>Fatal hepatocellular carcinoma presenting with oral metastasis in a patient with synchronic primary malignancies of prostate and liver</title><title>Gerodontology</title><addtitle>Gerodontology</addtitle><description>Background
Hepatocellular carcinoma (HCC) is the most frequent type of liver cancer and its occurrence in the oral cavity as a metastatic neoplasm is a rare event. We describe a fatal case of HCC with oral metastasis in a patient firstly diagnosed with prostatic and hepatic carcinomas. The histopathological examination revealed a hepatocyte‐like tumour cells arranged in organoid structures as well as positivity to cytokeratin 8 and Hep Par 1. The present findings highlight the importance of a complete medical evaluation of the patient to identify possible oral repercussions of primary diseases.</description><subject>Aged</subject><subject>Carcinoma, Hepatocellular - secondary</subject><subject>Fatal Outcome</subject><subject>hepatocellular carcinoma</subject><subject>Humans</subject><subject>immunohistochemistry</subject><subject>Liver Neoplasms - pathology</subject><subject>Male</subject><subject>Mouth Mucosa - pathology</subject><subject>Mouth Neoplasms - secondary</subject><subject>Neoplasms, Second Primary - pathology</subject><subject>oral metastasis</subject><subject>Prostatic Neoplasms - pathology</subject><issn>0734-0664</issn><issn>1741-2358</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNp10NFKwzAUBuAgipvTC19AcutFtyTNmvVSxjaFgSB6XU7T0y2SpiPpHHsBn9top3eGQCB85-fwE3LL2ZjHM9mgH3Mh0uyMDLmSPBHpdHZOhkylMmFZJgfkKoR3xsRUifSSDIQSTCkphuRzCR1YusUddK1Ga_cWPNXgtXFtA3TnMaDrjNvQg-m2tPVRN9hBiNcEahyNCDoTUS_C0emtb53Rcdg04I-0AWs2Dpw2GGhbx_82jndIwVXUmg_01-SiBhvw5vSOyNty8Tp_TNbPq6f5wzrRIhdZUslZncuSzaacYS1TrmcKQckyVUppLKXMIUehleJ5VjLFuEQoda0zneWyEumI3Pe5Oq4QPNbFaceCs-K7yyJ2Wfx0Ge1db3f7ssHqT_6WF8GkBwdj8fh_UrFavPSRX1sxgXU</recordid><startdate>201706</startdate><enddate>201706</enddate><creator>Rodrigues, Maria Fernanda Setúbal Destro</creator><creator>Esteves, Carina Magalhães</creator><creator>Oliveira, Márcio Augusto</creator><creator>Andrade, Nathália Paiva</creator><creator>Sedassari, Bruno Tavares</creator><creator>Soares, Fernando Augusto</creator><creator>Nunes, Fabio Daumas</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>201706</creationdate><title>Fatal hepatocellular carcinoma presenting with oral metastasis in a patient with synchronic primary malignancies of prostate and liver</title><author>Rodrigues, Maria Fernanda Setúbal Destro ; Esteves, Carina Magalhães ; Oliveira, Márcio Augusto ; Andrade, Nathália Paiva ; Sedassari, Bruno Tavares ; Soares, Fernando Augusto ; Nunes, Fabio Daumas</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2926-d48f94b08510ef431c87ea74b3777ceb449a9e2c77196b07014eabcfc6c694d23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Aged</topic><topic>Carcinoma, Hepatocellular - secondary</topic><topic>Fatal Outcome</topic><topic>hepatocellular carcinoma</topic><topic>Humans</topic><topic>immunohistochemistry</topic><topic>Liver Neoplasms - pathology</topic><topic>Male</topic><topic>Mouth Mucosa - pathology</topic><topic>Mouth Neoplasms - secondary</topic><topic>Neoplasms, Second Primary - pathology</topic><topic>oral metastasis</topic><topic>Prostatic Neoplasms - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rodrigues, Maria Fernanda Setúbal Destro</creatorcontrib><creatorcontrib>Esteves, Carina Magalhães</creatorcontrib><creatorcontrib>Oliveira, Márcio Augusto</creatorcontrib><creatorcontrib>Andrade, Nathália Paiva</creatorcontrib><creatorcontrib>Sedassari, Bruno Tavares</creatorcontrib><creatorcontrib>Soares, Fernando Augusto</creatorcontrib><creatorcontrib>Nunes, Fabio Daumas</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Gerodontology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rodrigues, Maria Fernanda Setúbal Destro</au><au>Esteves, Carina Magalhães</au><au>Oliveira, Márcio Augusto</au><au>Andrade, Nathália Paiva</au><au>Sedassari, Bruno Tavares</au><au>Soares, Fernando Augusto</au><au>Nunes, Fabio Daumas</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fatal hepatocellular carcinoma presenting with oral metastasis in a patient with synchronic primary malignancies of prostate and liver</atitle><jtitle>Gerodontology</jtitle><addtitle>Gerodontology</addtitle><date>2017-06</date><risdate>2017</risdate><volume>34</volume><issue>2</issue><spage>272</spage><epage>275</epage><pages>272-275</pages><issn>0734-0664</issn><eissn>1741-2358</eissn><abstract>Background
Hepatocellular carcinoma (HCC) is the most frequent type of liver cancer and its occurrence in the oral cavity as a metastatic neoplasm is a rare event. We describe a fatal case of HCC with oral metastasis in a patient firstly diagnosed with prostatic and hepatic carcinomas. The histopathological examination revealed a hepatocyte‐like tumour cells arranged in organoid structures as well as positivity to cytokeratin 8 and Hep Par 1. The present findings highlight the importance of a complete medical evaluation of the patient to identify possible oral repercussions of primary diseases.</abstract><cop>England</cop><pmid>27207742</pmid><doi>10.1111/ger.12236</doi><tpages>4</tpages></addata></record> |
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subjects | Aged Carcinoma, Hepatocellular - secondary Fatal Outcome hepatocellular carcinoma Humans immunohistochemistry Liver Neoplasms - pathology Male Mouth Mucosa - pathology Mouth Neoplasms - secondary Neoplasms, Second Primary - pathology oral metastasis Prostatic Neoplasms - pathology |
title | Fatal hepatocellular carcinoma presenting with oral metastasis in a patient with synchronic primary malignancies of prostate and liver |
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