Probiotic effect of Bifidobacterium longum 5 1A and Weissella paramesenteroides WpK4 on gerbils infected with Giardia lamblia

The objective of this study was to assess the probiotic potential of genuine strains of Bifidobacterium longum 5 and Weissella paramesenteroides WpK4, in experimental giardiasis. The bacteria were administered orally to gerbils (Meriones unguiculatus) 10 days before oral infection with trophozoites...

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Bibliographic Details
Published in:Journal of applied microbiology 2019-10, Vol.127 (4), p.1184-1191
Main Authors: Fonseca, J F, Alvim, L B, Nunes, Á C, Oliveira, F M S, Amaral, R S, Caliari, M V, Nicoli, J R, Neumann, E, Gomes, M A
Format: Article
Language:English
Subjects:
Animals
Bifidobacterium longum
Disease Models, Animal
Gerbillinae
Giardia lamblia - drug effects
Giardiasis
Parasite Load
Probiotics - pharmacology
Weissella
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Summary:The objective of this study was to assess the probiotic potential of genuine strains of Bifidobacterium longum 5 and Weissella paramesenteroides WpK4, in experimental giardiasis. The bacteria were administered orally to gerbils (Meriones unguiculatus) 10 days before oral infection with trophozoites of Giardia lamblia. After 7 days of infection, the animals were euthanized and portions of the duodenum were processed for histopathologic, histochemical and morphometric assessment. The height of the intestinal crypts and crypt/villi ratio were higher in infected groups (P 
ISSN:1364-5072
1365-2672
DOI:10.1111/jam.14338