Clinical utility of skin cancer and melanoma risk scores for population screening: TRoPICS study

Background Screening for skin cancer can be cost‐effective if focused on high‐risk groups. Risk prediction tools have been developed for keratinocyte cancers and melanoma to optimize advice and management. However, few have been validated in a clinical setting over the past few years. Objectives To...

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Bibliographic Details
Published in:Journal of the European Academy of Dermatology and Venereology 2021-05, Vol.35 (5), p.1094-1098
Main Authors: Shetty, A., Janda, M., Fry, K., Brown, S., Yau, B., Schuckmann, L. Von, Thomas, S., Rayner, J.E., Spelman, L., Wagner, G., Jenkins, H., Lun, K., Parbery, J., Soyer, H.P., Neale, R.E., Green, A.C., Whiteman, D.C., Olsen, C.M., Khosrotehrani, K.
Format: Article
Language:English
Subjects:
Adult
Carcinoma, Basal Cell - diagnosis
Carcinoma, Basal Cell - epidemiology
Early Detection of Cancer
Humans
Melanoma - diagnosis
Melanoma - epidemiology
Risk Factors
Sensitivity and Specificity
Skin Neoplasms - diagnosis
Skin Neoplasms - epidemiology
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Summary:Background Screening for skin cancer can be cost‐effective if focused on high‐risk groups. Risk prediction tools have been developed for keratinocyte cancers and melanoma to optimize advice and management. However, few have been validated in a clinical setting over the past few years. Objectives To assess the clinical utility of risk assessment tools to identify individuals with prevalent skin cancers in a volunteer‐based screening clinic. Methods Participants were adults presenting for a skin check at a volunteer‐based skin cancer screening facility. We used previously published tools, based on questionnaire responses, to predict melanoma and keratinocyte cancers [KCs; basal cell carcinoma (BCC) and squamous cell carcinoma (SCC)] and classified each participant into one of five risk categories. Participants subsequently underwent a full skin examination by a dermatologist. All suspicious lesions were biopsied, and all cancers were histopathologically confirmed. Results Of 789 people who presented to the clinic, 507 (64%) consented to the study. Twenty‐two BCCs, 19 SCCs and eight melanomas were diagnosed. The proportion of keratinocyte cancers diagnosed increased according to risk category from
ISSN:0926-9959
1468-3083
DOI:10.1111/jdv.17062