Increased risk of retinopathy of prematurity since increased O 2 saturation targets: A multi-centre study

Retinopathy of prematurity (ROP) is a leading cause of visual impairment in premature neonates. The BOOST II, SUPPORT and COT trials recommended increasing O saturation targets for pre-term neonates to reduce mortality; however, this is a risk factor for ROP. We aimed to determine whether these targ...

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Bibliographic Details
Published in:Journal of paediatrics and child health 2023-09, Vol.59 (9), p.1067-1074
Main Authors: Isaacs, Michael, Shah, Shaheen P, Dai, Shuan, Cartwright, David
Format: Article
Language:English
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Summary:Retinopathy of prematurity (ROP) is a leading cause of visual impairment in premature neonates. The BOOST II, SUPPORT and COT trials recommended increasing O saturation targets for pre-term neonates to reduce mortality; however, this is a risk factor for ROP. We aimed to determine whether these targets increased prevalence of ROP among pre-term neonates and higher risk groups. Retrospective cohort study conducted using data from the Australian and New Zealand Neonatal Network. 17 298 neonate cohort born 2012-2018 at
ISSN:1034-4810
1440-1754
DOI:10.1111/jpc.16456