Disseminated Transmissible Venereal Tumour Associated With L eishmaniasis in a Dog

This report addresses an atypical transmissible venereal tumour in an 8‐year‐old bitch that was pluriparous and seropositive for leishmaniasis. There were ascites and a serosanguineous discharge from the vulva, but no lesions on the external genital mucosa. An aspirate of the peritoneal fluid showed...

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Published in:Reproduction in domestic animals 2012-12, Vol.47 (s6), p.356-358
Main Authors: Trevizan, JT, Carreira, JT, Souza, NC, Carvalho, IR, Gomes, PBC, Lima, VMF, Orlandi, CMB, Rozza, DB, Koivisto, MB
Format: Article
Language:English
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Summary:This report addresses an atypical transmissible venereal tumour in an 8‐year‐old bitch that was pluriparous and seropositive for leishmaniasis. There were ascites and a serosanguineous discharge from the vulva, but no lesions on the external genital mucosa. An aspirate of the peritoneal fluid showed mononuclear round cells characteristic of transmissible venereal tumour ( TVT ). Exploratory laparotomy revealed light red, granulomatous structures in the peritoneum, omentum, spleen, liver and uterine horns. Cytological and histopathological tests confirmed the diagnosis of intra‐abdominal TVT . Dissemination of the TVT to several organs inside the abdominal cavity probably resulted from immunosuppression caused by leishmaniasis, which favoured the presence and aggressiveness of TVT .
ISSN:0936-6768
1439-0531
DOI:10.1111/rda.12110