Medical management of pneumoperitoneum, gastric pneumatosis, and hepatic venous gas secondary to 3% hydrogen peroxide toxicity in a dog

Objective To describe the medical management and outcome of a dog suffering severe hydrogen peroxide toxicity. Case Summary A 3‐year‐old neutered female Bichon Frise was presented to an emergency and referral practice after ingestion of 10–20 mL/kg 3% hydrogen peroxide. On presentation, the dog was...

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Bibliographic Details
Published in:Journal of veterinary emergency and critical care (San Antonio, Tex. : 2000) Tex. : 2000), 2024-03, Vol.34 (2), p.179-185
Main Authors: Gordon, Stefan B., Nadolski, Amy C.
Format: Article
Language:English
Subjects:
Aftercare
Animals
canine
Dog Diseases - chemically induced
Dog Diseases - therapy
Dogs
emetic
Female
Gastric Mucosa
gastric necrosis
hematemesis
Hydrogen Peroxide
hyperbaric oxygen
Patient Discharge
Pneumoperitoneum - chemically induced
Pneumoperitoneum - diagnostic imaging
Pneumoperitoneum - veterinary
Thoracic Injuries - veterinary
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Summary:Objective To describe the medical management and outcome of a dog suffering severe hydrogen peroxide toxicity. Case Summary A 3‐year‐old neutered female Bichon Frise was presented to an emergency and referral practice after ingestion of 10–20 mL/kg 3% hydrogen peroxide. On presentation, the dog was obtunded, was tachypneic, and had severe gastric tympany. Abdominal radiographs revealed pneumoperitoneum, gastric pneumatosis, and hepatic venous gas. The dog was managed conservatively with supportive care and oxygen therapy. Repeat radiographs 6 hours later showed complete resolution of all gas inclusions. While hospitalized, the dog developed severe hematemesis, and abdominal ultrasound revealed severe gastric wall thickening. Subsequent endoscopy confirmed severe gastric mucosal necrosis without evidence of deeper ulceration and relatively mild petechiation of the esophagus. The dog was ultimately discharged after 5 days of hospitalization and continued to do well at home. Recheck ultrasound 5 weeks postdischarge showed normal gastric wall appearance. New or Unique Information Provided To the authors’ knowledge, this is the first reported case of pneumoperitoneum secondary to hydrogen peroxide toxicity and the first description of the clinical course of severe toxicity in dogs.
ISSN:1479-3261
1476-4431
DOI:10.1111/vec.13363