Inter-spike mitochondrial Ca 2+ release enhances high frequency synaptic transmission

Presynaptic mitochondria not only absorb but also release Ca during high frequency stimulation (HFS) when presynaptic [Ca ] is kept low (

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Bibliographic Details
Published in:The Journal of physiology 2021-03, Vol.599 (5), p.1567-1594
Main Authors: Yang, Che Ho, Lee, Kyu-Hee, Ho, Won-Kyung, Lee, Suk-Ho
Format: Article
Language:English
Subjects:
Animals
Calcium - metabolism
Excitatory Postsynaptic Potentials
Mitochondria - metabolism
Rats
Sodium-Calcium Exchanger - metabolism
Synapses - metabolism
Synaptic Transmission
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Description
Summary:Presynaptic mitochondria not only absorb but also release Ca during high frequency stimulation (HFS) when presynaptic [Ca ] is kept low (
ISSN:0022-3751
1469-7793
DOI:10.1113/JP280351