Confocal microlaparoscope for imaging the fallopian tube

Recent evidence suggests that ovarian cancer can originate in the fallopian tube. Unlike many other cancers, poor access to the ovary and fallopian tubes has limited the ability to study the progression of this deadly disease and to diagnosis it during the early stage when it is most amenable to the...

Full description

Saved in:
Bibliographic Details
Published in:Journal of biomedical optics 2014-11, Vol.19 (11), p.116010-116010
Main Authors: Wu, Tzu-Yu, Rouse, Andrew R, Chambers, Setsuko K, Hatch, Kenneth D, Gmitro, Arthur F
Format: Article
Language:English
Subjects:
Biomedical materials
Cancer
Confocal
Equipment Design
Fallopian Tubes - chemistry
Fallopian Tubes - surgery
Female
Humans
Imaging
In vivo testing
In vivo tests
Laparoscopes
Laparoscopy - instrumentation
Laparoscopy - methods
Microscopy, Confocal - instrumentation
Microscopy, Confocal - methods
Optical Fibers
Research Papers: Imaging
Surgical implants
Tubes
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Recent evidence suggests that ovarian cancer can originate in the fallopian tube. Unlike many other cancers, poor access to the ovary and fallopian tubes has limited the ability to study the progression of this deadly disease and to diagnosis it during the early stage when it is most amenable to therapy. A rigid confocal microlaparoscope system designed to image the epithelial surface of the ovary in vivo was previously reported. A new confocal microlaparoscope with an articulating distal tip has been developed to enable in vivo access to human fallopian tubes. The new microlaparoscope is compatible with 5-mm trocars and includes a 2.2-mm-diameter articulating distal tip consisting of a bare fiber bundle and an automated dye delivery system for fluorescence confocal imaging. This small articulating device should enable the confocal microlaparoscope to image early stage ovarian cancer arising inside the fallopian tube. Ex vivo images of animal tissue and human fallopian tube using the new articulating device are presented along with in vivo imaging results using the rigid confocal microlaparoscope system.
ISSN:1083-3668
1560-2281
DOI:10.1117/1.JBO.19.11.116010