Effect of intraocular scattering in macular pigment optical density measurements

Fundus reflectometry is a common in-vivo, noninvasive method to estimate the macular pigment optical density (MPOD). The measured density, however, can be affected by the individual's intraocular scattering. Scattering causes a reduction in the contrast of the fundus image, which in turn leads...

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Bibliographic Details
Published in:Journal of biomedical optics 2018-05, Vol.23 (5), p.056001-056001
Main Authors: Christaras, Dimitrios, Pennos, Alexandros, Ginis, Harilaos, Artal, Pablo
Format: Article
Language:English
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Summary:Fundus reflectometry is a common in-vivo, noninvasive method to estimate the macular pigment optical density (MPOD). The measured density, however, can be affected by the individual's intraocular scattering. Scattering causes a reduction in the contrast of the fundus image, which in turn leads to an underestimation of the measured density. Intraocular scattering was measured optically in a group of seven young, healthy subjects using the method of optical integration and was subsequently used to correctly estimate the MPOD from fundus images. It was shown that when scattering is not considered, the measured optical density using fundus reflectometry can be underestimated by as high as 16% for our group of subjects.
ISSN:1083-3668
1560-2281
DOI:10.1117/1.JBO.23.5.056001