Improving environmental and stone factors toward a more realistic in vitro lithotripsy model

To improve in vitro lithotripsy models, we investigated the effects of multiple experimental variables on stone fragmentation. We performed timed burst wave lithotripsy (BWL) and shock wave lithotripsy (SWL) exposures in a water tank with the following variable parameters: water gas content (60, 30,...

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Bibliographic Details
Published in:The Journal of the Acoustical Society of America 2017-05, Vol.141 (5), p.3673-3674
Main Authors: Ahn, Justin, Kreider, Wayne, Hunter, Christopher, Zwaschka, Theresa, Bailey, Michael, Sorensen, Mathew, Harper, Jonathan, Maxwell, Adam D.
Format: Article
Language:English
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Summary:To improve in vitro lithotripsy models, we investigated the effects of multiple experimental variables on stone fragmentation. We performed timed burst wave lithotripsy (BWL) and shock wave lithotripsy (SWL) exposures in a water tank with the following variable parameters: water gas content (60, 30, and 15% O2), temperature (20 and 37°C), stone holder degree of enclosure (open wire basket, polyvinyl chloride (PVC) open-ended gel, and similar material anatomically accurate artificial kidney), and stone type (Begostone at 2 mixture ratios, calcite, calcium oxalate monohydrate (COM), and uric acid). At least 3 stones were treated for each condition, with fragmentation defined as percent stone mass
ISSN:0001-4966
1520-8524
DOI:10.1121/1.4987972