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In Vivo β-Secretase 1 Inhibition Leads to Brain Aβ Lowering and Increased α-Secretase Processing of Amyloid Precursor Protein without Effect on Neuregulin-1

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Bibliographic Details
Published in:The Journal of pharmacology and experimental therapeutics 2008-03, Vol.324 (3), p.957-969
Main Authors: Sankaranarayanan, Sethu, Price, Eric A., Wu, Guoxin, Crouthamel, Ming-Chih, Shi, Xiao-Ping, Tugusheva, Katherine, Tyler, Keala X., Kahana, Jason, Ellis, Joan, Jin, Lixia, Steele, Thomas, Stachel, Shawn, Coburn, Craig, Simon, Adam J.
Format: Article
Language:English
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ISSN:0022-3565
1521-0103
DOI:10.1124/jpet.107.130039