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The Identification of a Novel Phosphodiesterase 4 Inhibitor, 1-Ethyl-5-{5-[(4-methyl-1-piperazinyl)methyl]-1,3,4-oxadiazol-2-yl}- N -(tetrahydro-2 H -pyran-4-yl)-1 H -pyrazolo[3,4- b ]pyridin-4-amine (EPPA-1), with Improved Therapeutic Index using Pica Feeding in Rats as a Measure of Emetogenicity

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Bibliographic Details
Published in:	The Journal of pharmacology and experimental therapeutics 2009-09, Vol.330 (3), p.922-931
Main Authors:	Davis, T. Gregg, Peterson, John J., Kou, Jen-Pyng, Capper-Spudich, Elizabeth A., Ball, Doug, Nials, Anthony T., Wiseman, Joanne, Solanke, Yemisi E., Lucas, Fiona S., Williamson, Richard A., Ferrari, Livia, Wren, Paul, Knowles, Richard G., Barnette, Mary S., Podolin, Patricia L.
Format:	Article
Language:	English
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Online Access:	Get full text
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