Appearance of a Substance in Acute Phase Serum Which Elicits Cx-Protein Responses

Seromucoid was isolated from serum of rabbits during the acute inflammatory period following subcutaneous injection of an irritant and at times after whole body irradiation. It produced a Cx-protein response on intravenous injection into normal rabbits, an anamnestic response in immunized rabbits, l...

Full description

Saved in:
Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 1960-12, Vol.132 (3443), p.1894-1895
Main Authors: RILEY, R F, HOKAMA, Y
Format: Article
Language:English
Subjects:
Animals
Blood Proteins
Dosage
Endotoxins
Inflammation - blood
Intravenous injections
Leukocytes
Proteins
Rabbits
Radiation Effects
Vascular Diseases
Whole body irradiation
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Seromucoid was isolated from serum of rabbits during the acute inflammatory period following subcutaneous injection of an irritant and at times after whole body irradiation. It produced a Cx-protein response on intravenous injection into normal rabbits, an anamnestic response in immunized rabbits, leucocyte changes characteristic of inflammation, and marked toxicity in rabbits with reticuloendothelial system blockade. Normal seromucoid did not possess these properties.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.132.3443.1894