High Incidences of Transmissible Kidney Tumors in Uninoculated Frogs Maintained in a Laboratory

Various workers have shown that the Lucké carcinoma, a transmissible kidney tumor of the leopard frog, occurs spontaneously at low incidence (6.7 percent maximum). However, we have consistently observed much higher incidences (50 percent maximum), a finding of probable significance in the epidemiolo...

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 1961-03, Vol.133 (3454), p.702-703
Main Authors: Rafferty, Keen A., Rafferty, Nancy S.
Format: Article
Language:English
Subjects:
Histology
Kidneys
Nephrons
Tumors
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Summary:Various workers have shown that the Lucké carcinoma, a transmissible kidney tumor of the leopard frog, occurs spontaneously at low incidence (6.7 percent maximum). However, we have consistently observed much higher incidences (50 percent maximum), a finding of probable significance in the epidemiology and natural transmission of the tumor. Age, metabolic level, and cross infection are being investigated as possible factors in determining the tumor incidence.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.133.3454.702