C′3 Synthesis in the Human Fetus and Lack of Transplacental Passage

Allotypic differences in the third component of complement between mothers and their newborns provided evidence for synthesis of this complement component by the fetus. There was no indication that this protein traversed the placenta. The known low level of C′3 in the neonate was confirmed, and the...

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 1968-11, Vol.162 (3854), p.672-673
Main Authors: Propp, Richard P., Alper, Chester A.
Format: Article
Language:English
Subjects:
Fetus
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Summary:Allotypic differences in the third component of complement between mothers and their newborns provided evidence for synthesis of this complement component by the fetus. There was no indication that this protein traversed the placenta. The known low level of C′3 in the neonate was confirmed, and the maternal concentration was found to be significantly elevated.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.162.3854.672