Monosodium Glutamate: Absence of Hypothalamic Lesions after Ingestion by Newborn Primates

After receiving monosodium glutamate by stomach tube, the brains of infant macaques were perfused for examination by light and electron microscopy. No morphological differences were observed in the hypothalamic regions of treated and control monkeys. However, inadequately fixed tissue had the same a...

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 1971-06, Vol.172 (3990), p.1342-1344
Main Authors: Reynolds, W. Ann, Lemkey-Johnston, N., Filer, L. J., Pitkin, R. M.
Format: Article
Language:English
Subjects:
Animals
Animals, Newborn
Arcuate nucleus
Brain
Dendrites
Food Additives - toxicity
Glutamates - toxicity
Haplorhini
Hypothalamus - cytology
Hypothalamus - drug effects
Infants
Lesions
Microscopy, Electron
Monkeys
Monosodium glutamate
Neurons
Primates
Stomach
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Description
Summary:After receiving monosodium glutamate by stomach tube, the brains of infant macaques were perfused for examination by light and electron microscopy. No morphological differences were observed in the hypothalamic regions of treated and control monkeys. However, inadequately fixed tissue had the same appearance as that of the previously reported brain lesion in a newborn monkey.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.172.3990.1342