Prediction of the Spatial Distribution of Cell Survival in Heavy Ion Beams

The possible use of heavy ion beams for biomedical applications was examined through calculations of the physical beam properties and the spatial distribution of cell survival. Range straggling, creation of secondary particles, electron pickup, and the effects of inhomogeneous absorbers were analyze...

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 1971-12, Vol.174 (4014), p.1125-1127
Main Author: Vosburgh, Kirby G.
Format: Article
Language:English
Subjects:
Air forces
Bones
Cell Survival - radiation effects
Cells, Cultured - radiation effects
Energy
Heavy ions
Humans
Irradiation
Kidney - cytology
Models, Biological
Nitrogen
Nuclear interactions
Particle beams
Radiation Dosage
Radiation Effects
Radiotherapy
Tumors
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Summary:The possible use of heavy ion beams for biomedical applications was examined through calculations of the physical beam properties and the spatial distribution of cell survival. Range straggling, creation of secondary particles, electron pickup, and the effects of inhomogeneous absorbers were analyzed in terms of cell survival. Depth-survival plots for typical irradiations provide substantial encouragement for the investigation of these beams for biomedical applications in which localized tissue destruction is desired.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.174.4014.1125