Pharmacodynamic Evaluation of the Activity of Antibiotics against Hemin- and Menadione-Dependent Small-Colony Variants of Staphylococcus aureus in Models of Extracellular (Broth) and Intracellular (THP-1 Monocytes) Infections

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Published in:Antimicrobial Agents and Chemotherapy 2012-07, Vol.56 (7), p.3700-3711
Main Authors: GARCIA, L. G, LEMAIRE, S, KAHL, B. C, BECKER, K, PROCTOR, R. A, DENIS, O, TULKENS, P. M, VAN BAMBEKE, F
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents
Anti-Bacterial Agents - pharmacokinetics
Anti-Bacterial Agents - pharmacology
Antibiotics
Antibiotics. Antiinfectious agents. Antiparasitic agents
Bacterial diseases
Biological and medical sciences
Cell Line
Colony-forming cells
daptomycin
Daptomycin - pharmacokinetics
Daptomycin - pharmacology
Data processing
Drug resistance
Gentamicin
Gentamicins - pharmacokinetics
Gentamicins - pharmacology
Glycopeptides - pharmacokinetics
Glycopeptides - pharmacology
Hemin
Hemin - metabolism
Human bacterial diseases
Humans
Infection
Infectious diseases
Medical sciences
Menadione
Microbial Sensitivity Tests
Minimum inhibitory concentration
Monocytes
Monocytes - microbiology
Moxifloxacin
oritavancin
Phagocytosis
Pharmacodynamics
Pharmacology
Pharmacology. Drug treatments
Rifampin
Rifampin - pharmacokinetics
Rifampin - pharmacology
Staphylococcal Infections
Staphylococcal infections, streptococcal infections, pneumococcal infections
Staphylococcus aureus
Staphylococcus aureus - drug effects
Staphylococcus aureus - metabolism
Supplementation
Vancomycin
Vancomycin - pharmacokinetics
Vancomycin - pharmacology
Vitamin K 3
Vitamin K 3 - metabolism
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Summary:Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       
ISSN:0066-4804
1098-6596
DOI:10.1128/AAC.00285-12