Chronic Administration of Tenofovir to Rhesus Macaques from Infancy through Adulthood and Pregnancy: Summary of Pharmacokinetics and Biological and Virological Effects

• Published in: Antimicrobial Agents and Chemotherapy 2008-09, Vol.52 (9), p.3144-3160
• Main Authors: VAN ROMPAY, Koen K. A, DURAND-GASSELIN, Lucie, MARTHAS, Marta L, REISER, Hans, BISCHOFBERGER, Norbert, BRIGNOLO, Laurie L, RAY, Adrian S, ABEL, Kristina, CIHLAR, Tomas, SPINNER, Abigail, JEROME, Christopher, MOORE, Joseph, KEARNEY, Brian P
• Format: Article
• Language: English
• Subjects: Adenine - administration & dosage; Adenine - adverse effects; Adenine - analogs & derivatives; Adenine - pharmacokinetics; Adenine - therapeutic use; Age Factors; Animals; Anti-HIV Agents; Anti-HIV Agents - administration & dosage; Anti-HIV Agents - adverse effects; Anti-HIV Agents - pharmacokinetics; Anti-HIV Agents - therapeutic use; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antiviral Agents; Biological and medical sciences; Disease Models, Animal; Female; HIV Infections - drug therapy; HIV Infections - virology; HIV-1 - drug effects; Humans; Macaca mulatta; Medical sciences; Organophosphonates - administration & dosage; Organophosphonates - adverse effects; Organophosphonates - pharmacokinetics; Organophosphonates - therapeutic use; Pharmacology. Drug treatments; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Complications, Infectious - drug therapy; Pregnancy Complications, Infectious - virology; Reverse Transcriptase Inhibitors; Reverse Transcriptase Inhibitors - administration & dosage; Reverse Transcriptase Inhibitors - pharmacokinetics; Reverse Transcriptase Inhibitors - pharmacology; Reverse Transcriptase Inhibitors - therapeutic use; Simian Acquired Immunodeficiency Syndrome; Simian Acquired Immunodeficiency Syndrome - drug therapy; Simian Acquired Immunodeficiency Syndrome - virology; Simian Immunodeficiency Virus - drug effects; Simian Immunodeficiency Virus - physiology; Tenofovir; Time Factors; Treatment Outcome
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/aac.00350-08

Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • [e-mail] Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC