In Vitro Susceptibility of Clostridium difficile Clinical Isolates from a Multi-Institutional Outbreak in Southern Québec, Canada

Clostridium difficile isolates from a 2004 outbreak in Québec, Canada, were all found to be susceptible to metronidazole, vancomycin, rifampin, and meropenem but resistant to bacitracin, cefotaxime, ciprofloxacin, and levofloxacin, and most (>80%) were resistant to ceftriaxone, clarithromycin, g...

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Bibliographic Details
Published in:Antimicrobial agents and chemotherapy 2006-10, Vol.50 (10), p.3473-3475
Main Authors: Bourgault, Anne-Marie, Lamothe, François, Loo, Vivian G, Poirier, Louise
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents
Clostridium difficile
Disease Outbreaks
Enterocolitis, Pseudomembranous
Susceptibility
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Summary:Clostridium difficile isolates from a 2004 outbreak in Québec, Canada, were all found to be susceptible to metronidazole, vancomycin, rifampin, and meropenem but resistant to bacitracin, cefotaxime, ciprofloxacin, and levofloxacin, and most (>80%) were resistant to ceftriaxone, clarithromycin, gatifloxacin, and moxifloxacin. The predominant NAP1 isolates were susceptible to clindamycin, while the NAP2 isolates were resistant.
ISSN:0066-4804
1098-6596
DOI:10.1128/AAC.00479-06