Activity of the HIV-1 Attachment Inhibitor BMS-626529, the Active Component of the Prodrug BMS-663068, against CD4-Independent Viruses and HIV-1 Envelopes Resistant to Other Entry Inhibitors

• Published in: Antimicrobial Agents and Chemotherapy 2013-09, Vol.57 (9), p.4172-4180
• Main Authors: ZHUFANG LI, NANNAN ZHOU, YONGNIAN SUN, RAY, Neelanjana, LATAILLADE, Max, HANNA, George J, KRYSTAL, Mark
• Format: Article
• Language: English
• Subjects: Anti-HIV Agents; Anti-HIV Agents - pharmacology; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antibodies, Monoclonal - pharmacology; Antiviral Agents; Biological and medical sciences; CCR5 protein; CCR5 Receptor Antagonists; CD4 Antigens - metabolism; Cyclohexanes - pharmacology; Drug Resistance, Viral - drug effects; Enfuvirtide; HEK293 Cells; HIV Envelope Protein gp120 - metabolism; HIV Envelope Protein gp41 - pharmacology; HIV-1; HIV-1 - drug effects; HIV-1 - growth & development; HIV-1 - metabolism; Human immunodeficiency virus 1; Human viral diseases; Humans; Immunodeficiencies; Immunodeficiencies. Immunoglobulinopathies; Immunopathology; Infectious diseases; Maraviroc; Medical sciences; Organophosphates - metabolism; Organophosphates - pharmacology; Peptide Fragments - pharmacology; Pharmacology. Drug treatments; Piperazines; Piperazines - metabolism; Piperazines - pharmacology; Prodrugs - metabolism; Prodrugs - pharmacology; Receptors, CCR5 - metabolism; Receptors, CXCR4; Receptors, CXCR4 - antagonists & inhibitors; Receptors, CXCR4 - metabolism; Receptors, Virus; Receptors, Virus - antagonists & inhibitors; Receptors, Virus - metabolism; Triazoles; Triazoles - pharmacology; Viral diseases; Viral diseases of the lymphoid tissue and the blood. Aids; Virus Internalization; Virus Internalization - drug effects
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.00513-13

Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • [e-mail] Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC