Pharmacokinetics and Pharmacodynamics of TBR-652, a Novel CCR5 Antagonist, in HIV-1-Infected, Antiretroviral Treatment-Experienced, CCR5 Antagonist-Naïve Patients

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Published in:Antimicrobial Agents and Chemotherapy 2011-06, Vol.55 (6), p.2768-2774
Main Authors: MARIER, Jean-Francois, TRINH, Mymy, PHENG, Leng Hong, PALLEJA, Sandra M, MARTIN, David E
Format: Article
Language:English
Subjects:
Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome - drug therapy
Adult
Anti-HIV Agents
Anti-HIV Agents - pharmacokinetics
Anti-HIV Agents - pharmacology
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antiviral activity
Antiviral Agents
Azepines
Azepines - pharmacokinetics
Azepines - pharmacology
Biological and medical sciences
Blood
CCR5 protein
CCR5 Receptor Antagonists
Data processing
Dose-response effects
Dose-Response Relationship, Drug
Double-Blind Method
Female
HIV-1
Human immunodeficiency virus
Human immunodeficiency virus 1
Human viral diseases
Humans
Imidazoles
Imidazoles - pharmacokinetics
Imidazoles - pharmacology
Immunodeficiencies
Immunodeficiencies. Immunoglobulinopathies
Immunopathology
Infectious diseases
Male
Medical sciences
Middle Aged
Models, Biological
Pharmacodynamics
Pharmacokinetics
Pharmacology. Drug treatments
RNA
Statistical analysis
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
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Summary:OA  Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       
ISSN:0066-4804
1098-6596
DOI:10.1128/aac.00713-10