Epitope Switching as a Novel Escape Mechanism of HIV to CCR5 Monoclonal Antibodies

• Published in: Antimicrobial Agents and Chemotherapy 2010-02, Vol.54 (2), p.734-741
• Main Authors: JEKLE, Andreas, CHHABRA, Milloni, LOCHNER, Adriane, MEIER, Sonja, CHOW, Eugene, BRANDT, Michael, SANKURATRI, Surya, CAMMACK, Nick, HEILEK, Gabrielle
• Format: Article
• Language: English
• Subjects: Anti-HIV Agents; Anti-HIV Agents - pharmacology; Anti-HIV Agents - therapeutic use; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antibodies, Monoclonal; Antibodies, Monoclonal - pharmacology; Antibodies, Monoclonal - therapeutic use; Antiviral Agents; Binding Sites - genetics; Biological and medical sciences; Cell Line, Tumor; Cells, Cultured; Drug Resistance, Viral - genetics; Epitopes; Epitopes - chemistry; Epitopes - genetics; Epitopes - immunology; HIV; HIV - drug effects; HIV - genetics; HIV Infections; HIV Infections - drug therapy; HIV Infections - virology; Human immunodeficiency virus; Human viral diseases; Humans; Immunodeficiencies; Immunodeficiencies. Immunoglobulinopathies; Immunopathology; Infectious diseases; Medical sciences; Pharmacology. Drug treatments; Receptors, CCR5; Receptors, CCR5 - chemistry; Receptors, CCR5 - genetics; Receptors, CCR5 - immunology; Viral diseases; Viral diseases of the lymphoid tissue and the blood. Aids
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.00841-09

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