Low or High Doses of Cefquinome Targeting Low or High Bacterial Inocula Cure Klebsiella pneumoniae Lung Infections but Differentially Impact the Levels of Antibiotic Resistance in Fecal Flora

• Published in: Antimicrobial Agents and Chemotherapy 2014-03, Vol.58 (3), p.1744-1748
• Main Authors: VASSEUR, Maleck V, LAURENTIE, Michel, ROLLAND, Jean-Guy, PERRIN-GUYOMARD, Agnès, HENRI, Jérôme, FERRAN, Aude A, TOUTAIN, Pierre-Louis, BOUSQUET-MELOU, Alain
• Format: Article
• Language: English
• Subjects: Animals; Anti-Bacterial Agents; Anti-Bacterial Agents - administration & dosage; Anti-Bacterial Agents - pharmacology; Anti-Bacterial Agents - therapeutic use; Antibiotics. Antiinfectious agents. Antiparasitic agents; Bacterial Load; Biological and medical sciences; Cephalosporins; Cephalosporins - administration & dosage; Cephalosporins - pharmacology; Cephalosporins - therapeutic use; Drug Resistance, Bacterial - drug effects; Enterobacteriaceae; Escherichia coli; Experimental Therapeutics; Feces - microbiology; Klebsiella Infections; Klebsiella Infections - drug therapy; Klebsiella pneumoniae; Klebsiella pneumoniae - drug effects; Life Sciences; Male; Medical sciences; Medication; Pharmaceutical sciences; Pharmacology. Drug treatments; Pneumonia, Bacterial; Pneumonia, Bacterial - drug therapy; Rats
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.02135-13

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